RATIONAL IMMUNOGEN DESIGN
WHAT WE DO
Increasing pressure on healthcare systems highlight the need for new innovative approaches to disease prevention and treatment. We are developing new technologies to enable shorter development cycles and large scale manufacturability and increase the accessibility, affordability, durability, specificity, safety and effectiveness of immunotherapies for millions of patients worldwide.
BUILDING RATIONALLY OPTIMIZED IMMUNOTHERAPEUTIC DRUGS AND VACCINES
We employ a stream-lined process that integrates cutting edge technologies at the forefront of antigen discovery, protein design and drug development. Our rational immunotherapy design and engineering approach consists of two basic steps: Antigen engineering and nano formulation. Each step is highlighted below.
ANTIGEN ENGINEERING
We discover and modify target antigen sequences to optimize immunological properties and stabilize specific 3-D structures of key target epitopes. Our engineering approach build on the latest breakthroughs in bioinformatics, AI, computational drug design and protein engineering.
NANO FORMULATION
We apply breakthrough specifically tailored modular nanoparticles that present target antigens in an optimal geometry and contain specific immuno-modulatory components and adjuvants to potentiate and drive our target immune response towards a specific phenotype.
Shape Biopharmaceuticals Inc.
- 245 First St, Cambridge, MA 02142
- (617) 945 8640
- info@shapebiopharma.com